What role does genetics play in the development of cancer?
November 25, 2022 | 40,00 EUR | answered by Marie Hahn
Dear Doctor,
My name is Günther Altmayer and I recently received the diagnosis of cancer. This news has naturally unsettled me and I am thinking a lot about the causes of this disease. I am particularly interested in the role of genetics in the development of cancer.
There are some cases of cancer in my family, both on my parents' side and on my own. My maternal grandmother has breast cancer and my father had prostate cancer a few years ago. I wonder if these genetic predispositions could have also played a role in my case and if I have an increased risk for certain types of cancer.
I have heard that there are certain genetic mutations that can increase the risk of cancer. Can these mutations be tested for and what would that mean for me? Are there ways to reduce my personal risk for cancer if genetic factors are involved?
I am also worried about my children and grandchildren. Is cancer hereditary and how can I protect them from it? Are there preventive measures that we as a family can take to minimize the risk of cancer?
I would greatly appreciate it if you could explain to me more about the role of genetics in the development of cancer and possibly also about my personal risks due to my family history. Thank you in advance for your help.
Sincerely,
Günther Altmayer
Dear Mr. Altmayer,
First and foremost, I would like to offer my sincere condolences for the cancer diagnosis. It is understandable that this news is very unsettling and raises many questions. I would like to provide you with some information on the role of genetics in the development of cancer.
It is known that genetic factors can play a role in the development of cancer. Certain genetic mutations can increase the risk of developing certain types of cancer. These mutations can occur either in the so-called tumor suppressor genes, which control cell division, or in the oncogenes, which promote cell growth.
Regarding your family history, it is indeed possible that there is a genetic predisposition for cancer in your family. The fact that both your maternal grandmother and your father have been diagnosed with cancer suggests that genetic factors may be at play. It would be advisable to speak with a genetic counselor or an oncologist about genetic counseling in order to better assess your personal risk.
Genetic counseling can help you determine if you carry certain cancer genes and what impact this could have on your cancer risk. Depending on the results of the genetic test, measures for the prevention or early detection of cancer may be recommended.
It is important to emphasize that not all types of cancer are hereditary. However, a genetic predisposition can increase the risk for certain types of cancer. As a family, you may consider preventive measures such as a healthy lifestyle, regular check-ups, and avoiding risk factors such as smoking to minimize the risk of cancer.
Please do not hesitate to contact me with any further questions or to request a referral to a genetic counselor. It is important to be well-informed and take active measures to reduce risk.
I wish you strength and all the best on your journey.
Sincerely,
Marie Hahn, Oncology Specialist
